Ph.D. in Biomedical Science: Thematic Research Areas
Host-Pathogen Interactions and Immunology
Adam J. Adler,
Associate Professor of Immunology, B.S., McGill University, Ph.D.,
Columbia University. Our lab studies mechanisms of T cell tolerization
to peripheral self-antigens, as well as the relationship between
tolerance and tumor immunity.
H. Leonardo Aguila, Assistant Professor of
Immunology, Ph.D., Albert
Einstein College of Medicine. Hematopoiesis and bone marrow
microenvironment; lymphoid cell development; stem cell biology.
Choukri Ben
Mamoun, Ph.D., Associate Professor of Genetics and Developmental
Biology. Cell signaling and transport of nutrients in the human malaria
parasite plasmodium falciparum.
Stefan Brocke, Assistant Professor, M.D., Ph.D., Cellular
and molecular mechanisms of brain injury in inflammatory and
inflammation-associated disorders of the central nervous system.
Robert B. Clark,
Associate Professor of Immunology, M.D., Stanford, 1975. Autoimmunity;
immune regulation; regulatory T cells.
Robert E. Cone, Professor of
Immunology, B.S., Brooklyn College; M.S., Florida State University;
Ph.D., University of Michigan. Ocular immunology; regulatory T cells;
neuroimmunology.
Stephen J. Crocker, Assistant
Professor of Neuroscience, Ph.D., University of Ottowa.
Stem cells; glia; metalloproteinases; cytokines; development; pathology;
tissue culture.
Asis K. Das,
Professor of Molecular, Microbial and Structural Biology, B.Sc., M.Sc.,
Ph.D. University of Calcutta.
Genetics, genomics and
mechanisms of bacterial adaptive response; genetic control of
bacteriophage lysogeny and lysis; and non-coding RNAs in prokaryotic
development.
Anna
Dongari-Bagtzoglou, Assistant Professor of Periodontology, D.D.S.,
Aristotle University, Greece, M.S., University of California, Los
Angeles, Ph.D., University of Texas, San Antonio. Pathogenesis of oral
opportunistic infections in the immunocompromised host. Regulation of
oral mucosal inflammation in response to bacterial or fungal infection.
Innate immune factors which limit oral mucosal infection and invasion.
David I. Dorsky, Assistant Professor of Medicine, Division of
Infectious Diseases; M.D., Ph.D., Harvard, 1976.
Anti-HIV and anti-herpesvirus
drug mechanisms, herpesviral DNA polymerases, gene transfer strategies
applied to bioengineering and studies of antigen presentation.
Paul Epstein,
Ph.D., Associate Professor of Cell Biology. Receptor signal
transduction, second messengers, and protein phosphorylation in control
of cell growth and regulation; purification and regulation of cyclic
nucleotide phosphodiesterases; role of calmodulin in mediating Ca2+-dependent
cell processes.
Irving
Goldschneider, Professor of Immunology, B.A., M.D., University of
Pennsylvania. T and B cell development; acquired thymic tolerance;
cytokines.
Donald L.
Kreutzer, Professor of Pathology and Surgery, B.S., Colorado State
University; Ph.D., University of Kansas. Immunopathology and molecular
mechanisms of inflammation, mediators and regulators of leukocyte
chemotaxis, modulation of inflammatory reactions by the vascular
endothelium.
Leo
Lefrancois, Professor of Immunology, B.S., Colorado State
University; Ph.D., Wake Forest University. T-cell activation and
migration, T-cell memory; immune response to infection; tolerance;
vaccines.
Zihai (Zack) Li, Associate
Professor of Immunology and Medical Oncology, M.D., Henan Medical College, Ph.D., Mount Sinai School of Medicine. Member: Executive
Committee of the Department of Immunology and the Neag Comprehensive
Cancer Center. Tumor immunology, tolerance and innate immunity, roles of
heat shock proteins and Toll-like receptors in hematopoiesis and in the
functions of various immune cells in the mammalian system.
Bijay
Mukherji, Professor of Medicine, M.D., Calcutta University. Tumor
immunology and cancer vaccines, tumor-specific antigens.
Flavia A. O'Rourke, Assistant Professor of Cell Biology; Ph.D.,
Connecticut, 1976. Signal transduction in human platelets with specific
interest in the inositol phosphate signaling pathway and its regulation.
James O'Rourke, Professor of
Pathology, M.Sc., University of Pennsylvania; M.D., Georgetown
University. Vascular biology, tissue plasminogen activator synthesis,
transport and release.
Joel S. Pachter, Professor of
Cell Biology; Ph.D., NYU, 1983. Use of laser capture microdissection for
gene profiling of the neurovascular unit in health and disease.
Lynn
Puddington, Associate Professor of Immunology, B.S., Iowa State
University, Ph.D., Wake Forest University. Allergic asthma; neonatal
immunity and tolerance; developmental immunology.
Justin D.
Radolf, Professor of Medicine and Center for Microbial Pathogenesis,
M.D., University of California-San Francisco. Molecular pathogenesis and
immunobiology of spirochetal infections.
T.V. Rajan,
Professor and Interim Chairman of Pathology, Ph.D., Albert Einstein
College of Medicine; M.D., All India Institute of Medical Sciences.
Molecular immunoparasitology.
Pramod K.
Srivastava, Professor of Medicine, Ph.D., Center for Cellular &
Molecular Biology, Hyderabad, India. Heat shock proteins as peptide
chaperones, roles in antigen presentation and applications in
immunotherapy of cancer, infectious diseases and autoimmune disorders.
Jason M.
Tanzer, Professor and Division Head of Oral Medicine, Department of
Oral Diagnosis, School of Dental Medicine; also, Professor of Clinical
Microbiology, Department of Laboratory Medicine, School of Medicine. D.M.D. Tufts University School of Dental Medicine; Ph.D. Georgetown
University; D.H.C. Sahlgrenska Academy at the University of Gothenburg,
Sweden. 1. The physiological/biochemical/genetic bases of virulence by
the mutans streptococci (Streptococcus mutans) and its
colonization of the teeth and the physiological/biochemical/genetic
bases of non-virulence of Streptococcus gordonii despite its avid
colonization of the teeth. 2. The colonization determinants of certain
HIV-inhibiting Lactobacillus species in the
oral-gastro-intestinal tract.
Hung Ton-That,
Assistant Professor of Molecular, Microbial & Structural
Biology, B.S., Ph.D., University of California, Los Angeles. Pilus
assembly and sortase-mediated anchoring of surface proteins in
Gram-positive bacteria.
Roger S. Thrall,
Professor of Immunology, B.A., Eastern Connecticut State
College; Ph.D., Marquette University and Medical College of Wisconsin.
Immune cells, pulmonary inflammation.
Anthony T. Vella,
Assistant Professor of Immunology, Ph.D. Cornell University. T-cell
immunity; costimulation; adjuvants and cytokines.
Sandra K. Weller,
Professor of Molecular, Microbial and Structural Biology, B.S., Stanford
University, Ph.D., University of Wisconsin. Molecular genetics and
biochemistry of herpes simplex virus DNA replication.
Stephen K. Wikel,
Ph.D. Professor of Cell Biology and Immunology. The characterization of the complex
cellular and molecular immunology of the tick-host-pathogen interface.
Carol A. Wu,
Assistant Professor of Immunology, Ph.D. Vanderbilt University. Viral
respiratory infections and asthma.
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