Molecular Biology and Biochemistry Graduate Program

Research Facilities

The Molecular Biology and Biochemistry program offers complete and state-of-the-art research facilities within the Department of Molecular, Microbial and Structural Biology with equipment and expertise for genetic, biochemical, molecular, cellular, structural and biophysical investigation. Within the department are facilities for cell culture, fermentation systems for high volume growth of bacteria and yeast, FPLC and HPLC, and a biophysics core facility which is equipped with a circular dichroism spectropolarimeter, an isothermal titration calorimeter, and multi-angle laser light scattering facilities. The Department also houses the UConn Health Center NMR Structural Biology Facility which includes cryoprobe-equipped 500 and 600 MHz NMR spectrometers. Additional NMR spectrometers (400 and 800 MHz) and X-ray crystallography facilities are planned for 2004–05. The Department also houses the UConn Health Center Structural Biology Computational Facility, which includes a bank of Mac and Linux desktop computers connected to ultra-fast servers with the latest structural biology software. Facilities are also available for confocal laser scanning microscopy and low-light-level imaging microscopy in the state-of-the-art Center for Cell Analysis and Modeling. Additional facilities included electron microscopy, mass spectroscopy, DNA oligonucleotide synthesis and sequencing, microarray technology, and a transgenic mouse facility.