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Cell Biology Graduate Program

Faculty

Andrew Arnold, M.D., Professor of Medicine and Genetics and Developmental Biology, Murray-Heilig Chair in Molecular Medicine, Director, Center for Molecular Medicine. Pathogenesis of parathyroid and other endocrine tumors, and role of the cyclin D1 oncogene in neoplasia, including breast cancer.

Rashmi Bansal, Assistant Professor of Neuroscience; Ph.D., Central Drug Research Institute, 1976. The developmental, cellular and molecular biology of oligodendrocytes (OLs).

Gordon G. Carmichael, Professor of Microbiology; Ph.D., Harvard, 1975. Regulation of gene expression in eukaryotes.

Joan M. Caron, Assistant Professor, Department of Cell Biology; Ph.D., University of Connecticut. Biochemical, cell biological and genetic approaches to examine the function of microtubules, and to identify new anti-microtubule drugs for use against cancer.

Kevin Claffey, Assistant Professor of Cell Biology; Ph.D., Boston University School of Medicine, 1989. Angiogenesis in cancer progression and metastasis; Vascular endothelial growth factor (VEGF) expression; Hypoxia-mediated gene regulation.

Robert B. Clark, Associate Professor of Medicine, Division of Rheumatic Diseases; M.D., Stanford, 1975. Autoimmunity and tumor immunology.

Ann Cowan, Associate Professor of Molecular, Microbial and Structural Biology; Deputy Director, Center for Biomedical Imaging Technology; Ph.D., University of Colorado, 1984 Research encompassing several areas of mammalian sperm development.

Anne Delany, Assistant Professor of Medicine. Ph.D., Dartmouth Medical School. Function and regulation of the non-collagen matrix protein osteonectin/SPARC in bone; regulation of osteoblast gene expression by microRNAs; exploring how the extracellular matrix regulates gene expression in bone-metastatic prostate carcinoma.

Kimberly Dodge-Kafka, Assistant Professor of Cell Biology/Center for Cardiology and Cardiovascular Research; Ph.D., University of Texas Health Science Center-Houston, 1999. Molecular mechanism of signaling pathways in the heart.

David I. Dorsky, Associate Professor of Medicine, Division of Infectious Diseases; M.D., Ph.D., Harvard, 1976. The structure and function of herpes virus DNA polymerases and their roles in viral DNA replication.

Paul Epstein, Ph.D., Molecular biology of phosphodiesterases controlling cAMP.

Alan Fein, Professor of Cell Biology; Ph.D., Johns Hopkins, 1973. Molecular basis of visual excitation and adaptation.

Maurice B. Feinstein, Professor of Cell Biology; Ph.D., SUNY Downstate Medical Center, 1960. Role of blood platelet proteins in thromboembolic diseases (e.g., heart attack, stroke).

Guo-Hua Fong, Assistant Professor of Cell Biology, Ph.D., University of Illinois. Developmental biology of the vascular system, VEGF-A receptor signal transduction, embryonic stem cells and gene knock-out in mice.

Henry M. Furneaux, Associate Professor of Biochemistry; Ph.D., University of Aberdeen, Scotland. The regulation of gene expression at the posttranscriptional level.

Brenton R. Graveley, Assistant Professor Department of Genetics and Developmental Biology. Ph.D., University of Vermont, 1996. Regulation of alternative pre-mRNA splicing.

David Han, Assistant Professor, Ph.D., Washington University, 1994. Apoptosis signaling using proteomics and mass spectrometry and bioinformatics technologies.

Marc Hansen, Professor of Medicine, M.S., University of Wisconsin 1982, Ph.D. University of Cincinnati College of Medicine 1986. Molecular genetics of osteosarcoma and related bone diseases.

Greg Huber, Assistant Professor of Cell Biology, Ph.D., Boston University. Problems in biological physics, with an emphasis on the interplay of statistical mechanics, biomechanics, and fluid dynamics.

Marja Hurley, Associate Professor of Medicine, M.D., University of Connecticut School of Medicine. Molecular mechanisms by which members of the fibroblast growth factor (FGFs) and fibroblast growth factor receptor (FGFR) families, (produced by osteoblasts, osteoclasts and stromal cells) regulate bone development, remodeling and disorders of bone. Fgf2 knockout and Fgf2 transgenic mice are utilized in loss and gain of function experiments to elucidate the role of FGF-2 in disorders of bone including osteoporosis.

Laurinda A. Jaffe, Professor of Cell Biology; Ph.D., UCLA, 1977. The cell biology of fertilization, and the regulation of meiosis in oocytes.

Ingela Jansson, Ph.D., DNA-binding proteins in metallothionine induction and Cytochrome P450-cytochrome b5 interactions.

Stephen M. King, Associate Professor of Biochemistry; Ph.D., University College, London, 1982. Cell biology, structure and function of molecular motors, dynein biochemistry and cell biology, structural biology.

Dennis E. Koppel, Professor of Biochemistry; Ph.D., Columbia, 1973. Application of biophysical techniques to membrane dynamics; mechanisms by which specialized cell-surface domains are produced and maintained.

Eric S. Levine, Associate Professor of Neuroscience, Ph.D., Princeton University. Synaptic physiology and plasticity, roles of nerve growth factors and endogenous cannabinoids in hippocampus and cortex.

Bruce Liang, Professor of Cardio-Pulmonary, M.D., Harvard Medical School, 1982. Signal transduction, cardiac and vascular cell biology, receptors, G proteins, transgenic mice.

Leslie M. Loew, Professor of Cell Biology; Ph.D., Cornell, 1974. Spectroscopic methods for measuring spatial and temporal variations in membrane potential; electric field effects on cell membranes; membrane pores induced by toxins and antibiotics.

Nilanjana Maulik, Associate Professor of Surgery; Ph.D., University of Calcutta, 1990. Molecular and Cellular signaling during myocardial ischemia and reperfusion.

Lisa M. Mehlmann, Assistant Professor of Cell Biology, Ph.D., Kent State University, 1996. Cell signaling events that regulate oocyte maturation and fertilization, maintenance of oocyte meiotic arrest by G-protein coupled receptors, hormonal regulation of oocyte maturation.

Flavia A. O'Rourke, Assistant Professor of Cell Biology; Ph.D., Connecticut, 1976. Signal transduction in human platelets with specific interest in the inositol phosphate signaling pathway and its regulation.

Joel S. Pachter, Professor of Cell Biology; Ph.D., NYU, 1983. Elucidate the mechanisms by which leukocytes and pathogens invade the central nervous system.

Achilles Pappano, Ph.D. Cardiac membrane receptors and regulation of ion channels.

John J. Peluso, Professor of Cell Biology and Obstetrics and Gynecology, Ph.D., West Virginia University, 1974. Hormonal control of ovarian follicular growth and atresia (apoptosis); characterization of a putative membrane receptor for progesterone.

Carol C. Pilbeam, Associate Professor of Medicine; Ph.D., Yale University, 1982. M.D., Yale School of Medicine. Mechanisms of regulation of bone formation and resorption.

Vladimir Rodionov, Assistant Professor of Cell Biology; Ph.D., Moscow State University, 1980. Research in this laboratory is focused on molecular mechanisms of intracellular transport and organization of microtubule cytoskeleton.

Daniel W. Rosenberg, Ph.D., Associate Professor of Medicine. Molecular genetics of colorectal cancer; signaling pathways in the development of tumors; toxicogenomics.

David W. Rowe, Professor of Genetics and Developmental Biology; M.D., Vermont, 1969. Hormonal and genetic regulation of Type I collagen synthesis in bone, using molecular biological techniques.

John B. Schenkman, Professor of Cell Biology; Ph.D., SUNY Upstate Medical Center, 1964. Isolation and characterization of cytochrome P450 forms in mammalian tissues, mechanism of action of cytochrome P450, protein-protein interaction in the monoxygenase reaction.

Linda Shapiro, Associate Professor of Cell Biology; Ph.D., University of Michigan 1984. Molecular mechanisms by which large cell surface peptidases regulate numerous pathologic processes ranging from angiogenesis, tumor cell invasion, chronic and acute inflammatory diseases and cardiovascular disease.

Mark R. Terasaki, Associate Professor of Cell Biology, Ph.D., University of California, Berkeley, 1983. Mechanism of nuclear envelope breakdown; structure and function of the endoplasmic reticulum.

Jennifer Tirnauer, Assistant Professor of Medicine/Center for Molecular Medicine; M.D., University of Maryland School of Medicine, 1989. Role of the microtubule cytoskeleton in cancer biology; molecular mechanisms of microtubule regulation.

James Watras, Associate Professor of Medicine; Ph.D., Washington State, 1979. The mechanisms by which the sarcoplasmic reticulum regulates intracellular calcium concentration in vascular smooth muscle.

Bruce A. White, Professor of Cell Biology; Ph.D., Berkeley, 1980. Aspects of prolactin and growth hormone gene expression in the rat pituitary and rat pituitary tumor cell lines.

Charles Wolgemuth, Assistant Professor of Cell Biology; Ph.D., University of Arizona. My research objectives deal with using physics to understand biological systems. My main interests lie in morphology, propulsion, growth and fluid dynamics.

Catherine H. Wu, Professor of Medicine; Ph.D., CUNY, Brooklyn, 1976. Molecular control mechanisms involved in the regulation of collagen synthesis at a molecular level.

George Y. Wu, Professor of Medicine; M.D./Ph.D., Yeshiva (Einstein), 1976. Use of receptor-mediated endocytosis as a natural mechanism for targeting substances to specific cell-types.

Lixia Yue, Assistant Professor of Cell Biology, Center for Cardiology and Cardiovascular Biology; Ph.D., McGill University, 1999. TRP channels and Ca2+ signaling mechanisms; Physiological and pathological functions of TRP channels in heart, brain, and kidney.

  
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