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Faculty

Jason M. Tanzer
Professor of Oral Health and Diagnostic Sciences
Professor, Division of Clinical Microbiology, Department of Laboratory Medicine
Head, Division of Oral Microbiology/Oral Medicine
tanzer@nso.uchc.edu

  • D.M.D., Tufts University School of Dental Medicine
  • Ph.D., Georgetown University, Graduate School
  • D.H.C. (Doctor Honoris Causa), Sahlgrenska Academy at the University of Gothenburg, Sweden
  • Skeletal, Craniofacial & Oral Biology Graduate Program
  • Not accepting students for Lab Rotations at this time

Our laboratory is currently studying:

  1. The physiological/biochemical/genetic bases of virulence by the mutans streptococci (Streptococcus mutans) and its colonization of the teeth and the physiological/biochemical/genetic bases of non-virulence of Streptococcus gordonii despite its avid colonization of the teeth.
  2. The colonization determinants of certain HIV-inhibiting Lactobacillus species in the oral-gastrointestinal tract.

Selected Publications:

Tanzer JM, Grant L, Thompson A, Li L, Rogers J, Haase E, Scannapieco FA. Amylase-binding proteins A (AbpA) and B (AbpB differentially affect colonization of rats’ teeth by Streptococcus gordonii. Microbiology 149:2653-60, 2003.

Tanzer JM, Pellegrino J, Thompson AM, and Buch RM. Verification of caries inhibition by a tartar control toothpaste. J Clin Dent 14:74-6, 2003.

Tao L and Tanzer JM. Novel sucrose-dependent cofactors in Streptococcus mutans. J Dent Res 81:505-10, 2002.

Li L, Tanzer JM, Scannapieco FA. Identification and analysis of the amylase-binding protein B (AbpB) and gene (abpA) from Streptococcus gordonii. FEMS Letters 212:151-157, 2002.

Tanzer, J.M., Livingston, J., and Thompson, A. The microbiology of primary dental caries. Consensus Development Conference on the Diagnosis & Management of Dental Caries Throughout Life. National Institute of Dental and Craniofacial Research and Office of Medical Applications of Research, National Institutes of Health. Abbreviated Paper, J Dent. Educ. 65:1028-1037,2001.

Tanzer J.M., Baranowski L.K., Rogers J.D., Haase E.M., and Scannapieco F.A. Streptococcus gordonii colonizes TAN:SPFOM(OM)BR rats consuming a starch or sucrose diet, and is cariogenic only with the sucrose diet. Arch Oral Biol. 46:323-333,2001.

Tanzer, J.M., Pellegrino, J., Buch R.M., and Fares, H.M.: Caries inhibition in rats by a sodium fluoride, tripolyphosphate toothpaste with whitening and anti-tartar properties. J. Clin. Dent. 12(4):108-111, 2001.

Tanzer, J.M., Livingston, J., and Thompson, A. The microbiology of primary dental caries. Full paper. Consensus Development Conference on the Diagnosis & Management of Dental Caries Throughout Life. National Institute of Dental and Craniofacial Research and Office of Medical Applications of Research, National Institutes of Health. Full Paper, p. 1-42, exclusive of Evidence Tables, (~252 pages). http://www.nidcr.nih.gov/news/consensus/jason_tanzer.pdf

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