Areas of Interest
Limb development; roles and relationships among regulatory
genes particularly homeobox-containing genes, secreted signaling
molecules, and the extracellular matrix in the regulation of
limb formation, outgrowth, patterning, cartilage
differentiation, osteogenesis, and joint formation.
Selected Publications
Ferrari, D. and Kosher, R.A. (2002). Dlx5 is a positive
regulator of chondrocyte differentiation during endochondral
ossification. Dev. Biol. 252, 257-270.
Lizarraga, G., Lichtler, A., Upholt, W.B., and Kosher, R.A.
(2002). Studies on the role of Cux1 in regulation of the onset
of joint formation in the developing limb. Dev. Biol 243, 44-54.
Seghatoleslami, M.R., Martinez, A., Cuttitta, F., and Kosher,
R.A. (2002). Distribution and possible function of an
adrenomedulllin-like peptide in the developing chick limb bud.
Int. J. Dev. Biol. 46,957-961.
Tadic, T., Dodig, M., Erceg, I., Marijanovic, I., Mina, M.,
Kalajzic, Z., Velonis, D., Kronenberg, M.R., Ferrari, D.,
Kosher, R.A., and Lichtler, A.C. (2002). Overexpression of Dlx5
in chicken calvarial cells accelerates osteoblastic
differentiation. J. Bone Mineral Res. 17, 1008-1014.
Harrington, A., Dealy, C. N., and Kosher, R. A. (1999). Dlx-5
in limb initiation in the chick embryo. Developmental Dynamics
216, 10-15.
Lizarraga, G., Ferrari, D., Kalinowsky, M., Ohuchi, H., Noji,
S., Kosher, R.A., and Dealy, C.N. (1999). FGFR2 signaling in
normal and limbless chick limb buds. Developmental Genetics
25,331-338. |
