Ph.D. in Biomedical Science: Area of Concentration
Genetics & Developmental Biology
Faculty
Hector Leonardo Aguila,
Ph.D., Albert Einstein College of Medicine, Assistant
Professor of Immunology. Hematopoiesis and bone marrow microenvironment; lymphoid cell
development; stem cell biology.
Alexander
Amerik, M.S., Ph.D., Role of the ubiquitin system in protein
degradation and sorting.
Andrew Arnold,
M.D., Professor of Medicine and Genetics and Developmental Biology,
Murray-Heilig Chair in Molecular Medicine. The molecular genetic
underpinnings of tumors of the endocrine glands. Role of cyclin D1 in
tumorigenesis.
Choukri Ben
Mamoun, Ph.D., Associate Professor, Genetics and Developmental
Biology. Cell signaling and transport of nutrients in the human malaria
parasite plasmodium falciparum.
Peter Benn,
Ph.D., Director, Diagnostic Human Genetics Laboratories.
Clinical cytogenetics,
molecular cytogenetics and molecular genetics services. Prenatal risk
evaluation through maternal serum screening.
Gordon
Carmichael, Ph.D., Professor of Molecular, Microbial
& Structural Biology, Regulation of gene expression in
eukaryotes.
Kevin Claffey,
Ph.D, Associate Professor of Physiology. Angiogenesis in cancer
progression and metastasis; Vascular endothelial growth factor (VEGF)
expression; Hypoxia-mediated gene regulation.
Stephen Clark,
Ph.D., Associate Professor of Genetics and Developmental Biology.
Characterization of mutations affecting connective tissues; molecular
genetic mapping; generation and analysis of transgenic mice.
Asis K. Das,
Professor of Molecular, Microbial and Structural Biology, B.Sc., M.Sc.,
Ph.D. University of Calcutta.
Genetics, genomics and
mechanisms of bacterial adaptive response; genetic control of
bacteriophage lysogeny and lysis; and non-coding RNAs in prokaryotic
development.
Caroline N.
Dealy, Ph.D., Associate Professor of Biostructure and Function.
The molecular regulation of limb
development in the vertebrate embryo, from early stages where the limb
is initially formed, to limb patterning and outgrowth, to skeletogenesis.
Paul Epstein,
Ph.D., Associate Professor of Pharmacology. Receptor signal
transduction, second messengers, and protein phosphorylation in control
of cell growth and regulation; purification and regulation of cyclic
nucleotide phosphodiesterases; role of calmodulin in mediating Ca2+-dependent
cell processes.
Min Fang,
M.D., Ph.D., Assistant Professor of
Genetcis and Developmental Biology. The
role of early growth response gene 1 (EGR1) in tumorigensis.
Guo-Hua Fong,
Ph.D., Assistant Professor of Cell Biology. Developmental biology of the
vascular system, VEGF-A receptor signal transduction, embryonic stem
cells and gene knock-out in mice.
Brenton R.
Graveley, Ph.D., Associate Professor of Genetics and Developmental
Biology. Regulation of alternative pre-mRNA splicing.
Arthur Günzl,
Ph.D., Associate Professor of Genetics and Developmental Biology and
Center for Microbial Pathogenesis. Transcription and Antigenic Variation
in the mammalian parasite Trypanosoma brucei.
Marc Hansen,
Ph.D., Professor of Medicine. Molecular genetics of osteosarcoma and
related bone diseases.
Timothy Hla,
Ph.D., Professor of Cell Biology. Molecular mechanisms of
angiogenesis, G-protein-coupled receptor signaling, Cyclooxygenase
(Cox-2) and cancer, lipid mediators
Laurinda Jaffe,
Ph.D., Professor of Cell Biology. The cell biology of fertilization, and
the regulation of meiosis in oocytes.
Robert A.
Kosher, Ph.D., Professor Department of Biostructure and Function.
Limb development; roles and relationships among regulatory genes
particularly homeobox-containing genes, secreted signaling molecules,
and the extracellular matrix in the regulation of limb formation,
outgrowth, patterning, cartilage differentiation, osteogenesis, and
joint formation.
Barbara Kream,
Ph.D., Professor of Medicine and Genetics and Developmental Biology.
Hormonal regulation of bone remodeling.
George Kuchel,
M.D., Professor of Medicine. Role of hormones
and cytokines in geriatric disability. Pathogenesis of impaired detrusor
contractility and urinary retention. Molecular mechanisms of bladder
muscle survival.
Marc Lalande,
Ph.D. Professor and Head of Genetics and Developmental Biology. Epigenetics
including the control of gene expression in embryonic carcinoma stem
cells and genomic imprinting and its association with neurogenetics
disorders.
James Li, Ph.D., Assistant
Professor. Mechanisms underlying normal and abnormal development
of the central nervous system; stem cell biology.
Alexander
Lichtler, Ph.D., Associate Professor of Genetics and Developmental
Biology. Regulation of collagen gene transcription; retrovirus vectors;
role of homeobox genes in limb development.
Bruce J. Mayer,
Associate Professor of Genetics and Developmental Biology, Ph.D.
Rockefeller University, Mechanisms of signal transduction.
Mina Mina,
D.M.D, PhD., Professor of Pediatric Dentistry. Characterization of
genetic and epigenetic influences involved in pattern formation and
skeletogenesis of the chick mandible and mouse tooth germ.
William A.
Mohler, Ph.D., Assistant Professor of Genetics and Developmental
Biology. Developmental cell fusion; C. elegans genetics;
multidimensional imaging of developmental and cell biological processes.
D. Kent Morest,
M.D., Professor of Neuroscience. Role of cell and tissue interactions in
the migration and differentiation of neurons; structure and function of
neurons during development and synapse formation.
John J. Peluso,
Ph.D., Professor of Cell Biology. Hormonal control of ovarian follicular
growth and atresia (apoptosis); characterization of a putative membrane
receptor for progesterone.
Carol C. Pilbeam, Professor of Medicine; PhD., Yale University,
1982. M.D., Yale School of Medicine. Mechanisms of regulation of bone
formation and resorption.
Justin D.
Radolf, M.D., Professor of Medicine and Center for Microbial
Pathogenesis. Molecular pathogenesis and immunobiology of spirochetal
infections.
Blanka Rogina,
Assistant Professor of Genetics and Developmental Biology, Ph.D., Zagreb
Univ. School of Medicine. Biology of aging including the molecular
genetic determinants of aging and longevity.
Daniel W.
Rosenberg, Ph.D., Professor of Medicine. Molecular genetics of
colorectal cancer; signaling pathways in the development of tumors;
toxicogenomics
Edward F.
Rossomando, D.D.S., Ph.D., Professor of BioStructure and Function.
Control of gene expression in tumor and nontumor cell lines in response
to stimulation by monokines; coding, transmission, and processing of
environmental signals in normal and abnormal development.
David Rowe,
M.D., Professor of Genetics and Developmental Biology. Hormonal
regulation of Type I collagen in mature and developing bone; heritable
disorders of bone formation.
Mansoor
Sarfarazi, Ph.D., Professor of Surgery. Positional Mapping and
Mutation Analysis of Human Genetic Disorders; Primary Open Angle
Glaucoma, Primary Congenital Glaucoma, Synpolydactyly, Dyslexia, Mitral
Valve Prolapse and Ascending Aortic Aneurysm.
Petros
Tsipouras, M.D., Professor of Pediatrics. Heritable disorders of
connective tissue, nosology, and genetics; genetic linkage studies;
molecular mechanisms of mutations in human collagen genes.
William B.
Upholt, Ph.D., Professor of BioStructure and Function. Regulation of
gene expression during embryonic development; procollagen gene
expression and regulation in limb chondrogenesis and skeletogenesis;
pattern formation; homeobox genes.
Bruce White,
Ph.D., Professor of Cell Biology. Control of prolactin gene expression
at pretranslational level in GH3 cells; control of aromatase gene
expression in ovarian and testicular tissues.
Stephen K. Wikel,
Ph.D., Professor of Cell Biology. The characterization of the complex
cellular and molecular immunology of the tick-host-pathogen interface.
Ren-He Xu,
Associate Professor of Genetics and Developmental Biology and Director, Human Embryonic Stem Cell Facility, Ph.D., University of
Tokyo, M.D., Hengyang Medical College. The biology of human embryonic
stem cells. |
